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Article

Programmed -1 Ribosomal Frameshifting in coronaviruses: A therapeutic target.

Virology - 1 Feb 2021

Kelly Jamie A, Woodside Michael T, Dinman Jonathan D

Abstract excerpt

Human population growth, climate change, and globalization are accelerating the emergence of novel pathogenic viruses. In the past two decades alone, three such members of the coronavirus family have posed serious threats, spurring intense efforts to understand their biology as a way to identify targetable vulnerabilities. Coronaviruses use a programmed -1 ribosomal frameshift (-1 PRF) mechanism to direct...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33387787
DOI: 10.1016/j.virol.2020.12.010
PMCID: PMC7833279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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