Article
von Willebrand disease and pregnancy: a practical approach for the diagnosis and treatment.
American journal of obstetrics and gynecology - 1 Sept 2010
Pacheco Luis D, Costantine Maged M, Saade George R, Mucowski Sara, Hankins Gary D V, Sciscione Anthony C
Abstract excerpt
von Willebrand disease is caused by either a quantitative or qualitative defect in von Willebrand factor (VWF). Patients may have extensive mucosal bleeding (because of platelet dysfunction) and prolonged bleeding after surgery (because of factor VIII deficiency). Up to 6 different subtypes of the disease have been described, and diagnosis is based on clinical suspicion and laboratory confirmation. Accurate...
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