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Von Willebrand disease (VWD) and pregnancy: a comprehensive overview

28 Apr 2025

Abstract excerpt

Von Willebrand disease (VWD) is a hereditary bleeding disorder characterized by a quantitative or qualitative deficiency of von Willebrand factor (VWF). Pregnancy significantly impacts hemostasis, leading to a hypercoagulable state. However, women with VWD experience unique challenges due to the interplay between pregnancy-related hormonal changes and VWF deficiencies. This review delves into the intricate...

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PMID: 40296027
DOI: 10.1186/s12959-025-00727-7

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