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Article

Novel cage stress alters remote contextual fear extinction and regional T2 magnetic resonance relaxation times in TASTPM mice overexpressing amyloid.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Rattray Ivan, Pitiot Alain, Lowe James, Auer Dorothee P, Lima Sarah-Jane, Schubert Mirjam I, Prior Malcolm J W, Marsden Charles A, Diaz Fernando Pérez, Kendall David A, Pardon Marie-Christine

Abstract excerpt

We have previously shown that repeated exposure to mild novel cage stress prevents the onset of recent contextual fear memory deficits and attenuated amyloid deposition in the TASTPM mouse model of Alzheimer's disease. Here, we extended this investigation to remote contextual fear memory and extinction. TASTPM and wild-type mice acquired contextual fear at 4 months of age. Retention and extinction of contextual...

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Identifiers

PMID: 20413887
DOI: 10.3233/JAD-2010-091354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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