Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotype, compartmental organization and differential vulnerability of nigral dopaminergic neurons.

Journal of neural transmission. Supplementum - 1 Jan 2009

González-Hernández Tomás, Afonso-Oramas Domingo, Cruz-Muros Ignacio

Abstract excerpt

The degeneration of nigral dopaminergic (DA-) neurons is the histopathologic hallmark of Parkinson's disease (PD), but not all nigral DA-cells show the same susceptibility to degeneration. This starts in DA-cells in the ventrolateral and caudal regions of the susbtantia nigra (SN) and progresses to DA-cells in the dorsomedial and rostral regions of the SN and the ventral tegmental area, where many neurons remain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dopamine
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neurons

Share to Phenotype

Share to Substantia Nigra

Source

Identifiers

PMID: 20411765
DOI: 10.1007/978-3-211-92660-4_2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotype, compartmental organization and differential vulnerability of nigral dopaminergic neurons.PMID 20411765Read ↗

Dopamine across timescales and cell types: Relevance for phenotypes in Parkinson's disease progression.Semantic proximity Read ↗

Pathogenesis of nigral cell death in Parkinson's diseaseSemantic proximity Read ↗

Sex-dimorphic effects of neuromelanin buildup in rodent nigral dopamine neurons: implications for sex-biased vulnerability in Parkinson’s diseaseSemantic proximity Read ↗

Brain neurons partly expressing dopaminergic phenotype: location, development, functional significance, and regulation.Semantic proximity Read ↗

Dopaminergic neurons intrinsic to the striatum.Semantic proximity Read ↗

Death in the substantia nigra: a motor tragedySemantic proximity Read ↗

Non-dopaminergic neurons partly expressing dopaminergic phenotype: distribution in the brain, development and functional significance.Semantic proximity Read ↗

Strategies to unravel molecular codes essential for the development of meso-diencephalic dopaminergic neurons.Semantic proximity Read ↗

Dopamine Signaling in Substantia Nigra and Its Impact on Locomotor Function; Not a New Concept, but Neglected Reality Simmering in Striatal StewSemantic proximity Read ↗

Transcriptome responses to reduced dopamine in the Substantia Nigra Pars Compacta reveals a potential protective role for dopamineSemantic proximity Read ↗

The phenotype spectrum of Japanese multiple system atrophy.Semantic proximity Read ↗

Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.