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Article

Drug resistance, epigenetics, and tumor cell heterogeneity.

Science translational medicine - 21 Apr 2010

Hoey Timothy

Abstract excerpt

The resistance of cancer cells to various therapeutic agents and modalities is a crucial issue in clinical oncology. A recent Cell paper highlights how changes at the chromatin level control drug sensitivity and provides insight into more effective strategies for treating cancer with combination therapies.

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Share to Drug Resistance, Neoplasm
Share to Epigenesis, Genetic
Share to ErbB Receptors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genetic Heterogeneity

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Source

Identifiers

PMID: 20410528
DOI: 10.1126/scitranslmed.3001056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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