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Intratumoral Patterns of Genomic Imbalance in Glioblastomas

20 Mar 2010

Abstract excerpt

Glioblastomas are morphologically and genetically heterogeneous, but little is known about the regional patterns of genomic imbalance within glioblastomas. We recently established a reliable whole genome amplification (WGA) method to randomly amplify DNA from paraffin-embedded histological sections with minimum amplification bias [Huang et al (J Mol Diagn 11: 109-116, 2009)]. In this study, chromosomal imbalance...

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PMID: 20406234
DOI: 10.1111/j.1750-3639.2010.00395.x

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