Article
Spatial variability of genomic aberrations in a large glioblastoma resection specimen.
Acta neuropathologica - 1 Jul 2001
Kros J M, van Run P R, Alers J C, Avezaat C J, Luider T M, van Dekken H
Abstract excerpt
In the present study, the distribution of genetic aberrations in a glioblastoma resection specimen of unusually large size (9x8x2 cm) was investigated using comparative genomic hybridization (CGH). CGH was performed on 20 samples taken from the specimen, and the genetic aberrations found were compared with the regional histology. The samples were histopathologically graded according to WHO criteria, and a...
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