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Article

Time course of retinal degeneration associated with the absence of 1, 4, 5-inositol trisphosphate receptor in Drosophila melanogaster.

Experimental biology and medicine (Maywood, N.J.) - 1 Mar 2010

Vázquez-Martínez Olivia, Loranca Angélica, Palma-Tirado Lourdes, Wischin-Fuentes Sabina, Villalobos-Leal Mónica, Antaramián Anaid, Riesgo-Escovar Juan, Hernández-Muñoz Rolando, Díaz-Muñoz Mauricio

Abstract excerpt

The absence of the inositol trisphosphate receptor is associated with a gradual retinal degeneration in Drosophila melanogaster. To characterize the time-course profile of this process, mosaic flies expressing a null allele of the itp gene in the eye were studied by electroretinograms and electronic microscopy. Membrane contour alterations, disrupted mitochondria, altered morphology and even loss of...

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PMID: 20404055
DOI: 10.1258/ebm.2009.009300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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