Article
The effect of mobile element IS10 on experimental regulatory evolution in Escherichia coli.
Molecular biology and evolution - 1 Sept 2010
Stoebel Daniel M, Dorman Charles J
Abstract excerpt
Mobile genetic elements are widespread in bacteria, where they cause several kinds of mutations. Although their effects are on the whole negative, rare beneficial mutations caused by insertion sequence elements are frequently selected in some experimental evolution systems. For example, in earlier work, we found that strains of Escherichia coli that lack the sigma factor RpoS adapt to a high-osmolarity...
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