Article
Dynamics of bacterial insertion sequences: can transposition bursts help the elements persist?
BMC evolutionary biology - 21 Dec 2015
Wu Yue, Aandahl Richard Z, Tanaka Mark M
Abstract excerpt
BACKGROUND: Currently there is no satisfactory explanation for why bacterial insertion sequences (ISs) widely occur across prokaryotes despite being mostly harmful to their host genomes. Rates of horizontal gene transfer are likely to be too low to maintain ISs within a population. IS-induced beneficial mutations may be important for both prevalence of ISs and microbial adaptation to changing environments but may...
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