The spread of a beneficial mutation in experimental bacterial populations: the influence of the environment and genotype on the fixation of rpoS mutations.

Abstract excerpt

The spread of beneficial mutations through populations is at the core of evolutionary change. A long-standing hindrance to understanding mutational sweeps was that beneficial mutations have been slow to be identified, even in commonly studied experimental populations. The lack of information on what constitutes a beneficial mutation has led to many uncertainties about the frequency, fitness benefit and fixation...

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