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Article

Selective gene expression in failing human heart. Quantification of steady-state levels of messenger RNA in endomyocardial biopsies using the polymerase chain reaction.

1 Jun 1991

Abstract excerpt

BACKGROUND: Evaluation of gene expression in failing human heart has been limited by the availability of cardiac tissue. METHODS AND RESULTS: We used the polymerase chain reaction (PCR) to assess gene expression in small quantities of failing and nonfailing human heart. PCR is a powerful new molecular biological tool that allows a small quantity of DNA to be amplified as much as 1 million-fold. Total RNA was...

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Identifiers

PMID: 2040039
DOI: 10.1161/01.cir.83.6.1866

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Source receipt: pubmed, retrieved 7 Sept 2026.

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