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Article

Serial gene expression profiling in the intact human heart.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 May 2006

Lowes Brian D, Zolty Ronald, Minobe Wayne A, Robertson Alastair D, Leach Sonia, Hunter Lawrence, Bristow Michael R

Abstract excerpt

BACKGROUND: In chronic heart failure due to a dilated cardiomyopathy phenotype, the molecular bases for contractile dysfunction and chamber remodeling remain largely unidentified. METHODS: To investigate the feasibility of measuring global gene expression serially in the intact failing human heart, we performed repeated messenger RNA (mRNA) expression profiling using RNA extracted from endomyocardial biopsy...

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Source

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Identifiers

PMID: 16678038
DOI: 10.1016/j.healun.2006.01.006
PMCID: PMC2709530

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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