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Article

Hypertrophic cardiomyopathy mutation is expressed in messenger RNA of skeletal as well as cardiac muscle.

Circulation - 1 Feb 1993

Yu Q T, Ifegwu J, Marian A J, Mares A, Hill R, Perryman M B, Bachinski L L, Roberts R, Marlan A J

Abstract excerpt

BACKGROUND: The beta-myosin heavy chain (beta-MHC) gene has been identified as a major locus for familial hypertrophic cardiomyopathy (FHCM). We recently showed that one of the common mutations associated with FHCM is expressed in the cardiac muscle messenger RNA (mRNA) of an affected individual....

Topics

Adult
Alleles
Base Sequence
Cardiomyopathy, Hypertrophic
DNA
Humans
Middle Aged
Molecular Probes
Molecular Sequence Data
Muscles
Mutation
Papillary Muscles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

RNA, Messenger

Reference Values

Transcription, Genetic

Source

Identifiers

PMID: 8425289
DOI: 10.1161/01.cir.87.2.406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8425289-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Hypertrophic cardiomyopathy mutation is expressed in messenger RNA of skeletal as well as cardiac muscle.PMID 8425289Read ↗

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