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Article

POLG1 in idiopathic Parkinson disease.

Neurology - 14 Nov 2006

Tiangyou W, Hudson G, Ghezzi D, Ferrari G, Zeviani M, Burn D J, Chinnery P F

Abstract excerpt

We studied POLG1 in 140 UK patients with idiopathic Parkinson disease (PD) and 279 Italian patients with PD and compared them to a UK control group (n = 207) and an Italian control group (n = 285). Our observations do not support a role for common POLG1 genetic variants in PD and indicate that dominant POLG1 mutations are a rare cause of parkinsonism in the general population.

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Identifiers

PMID: 16943369
DOI: 10.1212/01.wnl.0000238963.07425.d5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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