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Article

A large deletion of PROP1 gene in patients with combined pituitary hormone deficiency from two unrelated Chinese pedigrees.

Hormone research in paediatrics - 1 Jan 2010

Zhang Huiwen, Wang Yi, Han Lianshu, Gu Xuefan, Shi Dingping

Abstract excerpt

BACKGROUND: Familial combined pituitary hormone deficiency (CPHD) appears to have a genetic cause, PROP1 gene mutations being the most common one. We investigated whether PROP1 plays a role in two Chinese familial cases of CPHD. METHODS: PROP1 gene and adjacent sequences from genomic samples from two unrelated families were amplified to investigate molecular variations and define the extension of a potential...

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Source

Identifiers

PMID: 20395664
DOI: 10.1159/000313375

Genes

PROP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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