Article
Tissue-specific and dexamethasone-inducible expression of alkaline phosphatase from alternative promoters of the rat bone/liver/kidney/placenta gene.
Biochemical and biophysical research communications - 15 May 1991
Zernik J, Kream B, Twarog K
Abstract excerpt
The rat Bone/Liver/kidney/Placenta Alkaline Phosphatase (ALP) is transcribed from two alternative promoters spaced over 25 kb apart, resulting in two variant transcripts that are identical in their coding sequence. We investigated the steady-state levels of the two variant transcripts in various...
Topics
- Alkaline Phosphatase
- Animals
- Bone and Bones
- Cell Line
- Dexamethasone
- Female
- Genes
- Kidney
- Liver
- Osteosarcoma
- Phenotype
- Placenta
- Polymerase Chain Reaction
- Pregnancy
- Promoter Regions, Genetic
- RNA, Messenger
- Rats
- Transcription, Genetic
