Col1a1-Driven Transgenic Markers of Osteoblast Lineage Progression

doi:10.1359/jbmr.2001.16.7.1228

Article

Col1a1-Driven Transgenic Markers of Osteoblast Lineage Progression

1 Jul 2001

Abstract excerpt

The modular organization of the type I collagen promoter allows creation of promoter-reporter constructs with preferential activity in different type I collagen-producing tissues that might be useful to mark cells at different stages of osteoblastic differentiation. Primary marrow stromal cell (MSC) and mouse calvarial osteoblast (mCOB) cultures were established from transgenic mice harboring different Col1a1...

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