Article
[Genetic markers in forensic medical examination of acute and chronic opioid intoxication].
Sudebno-meditsinskaia ekspertiza - 1 Jan 2000
Sorokina V V
Abstract excerpt
The objective of the present study was to analyse cases of intoxication with opioid narcotics at different blood morphine levels, from low and very low (below 0.5 mg/l) to regular toxic ones (1-4 mg/I). It was shown that molecular genetic studies at postmortem morphine concentrations of up to 0.5 mg/l as a rule identify mutant alleles (CYP2D6*3*4; CYP2C19*2*3). Mutant alleles CYP2D6* and CYP2C19* are most...
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