Article
[Genetic polymorphism and drug interactions: their importance in the treatment of pain].
Canadian journal of anaesthesia = Journal canadien d'anesthesie - 1 Oct 2005
Samer Caroline F, Piguet Valérie, Dayer Pierre, Desmeules Jules A
Abstract excerpt
OBJECTIVES: To evaluate the impact of certain genetic polymorphisms on variable responses to analgesics SOURCES: Systematic review, by means of a structured computerized search in the Medline database (1966-2004). Articles in English and French were selected. References in relevant articles were also retrieved. MAIN FINDINGS: Most analgesics are metabolized by CYP isoenzymes subject to genetic polymorphism....
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