Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oxycodone findings and CYP2D6 function in postmortem cases.

Forensic science international. Genetics - 1 Jul 2021

Jakobsson Gerd, Larsson Ronja, Pellè Lucia, Kronstrand Robert, Gréen Henrik

Abstract excerpt

Genetic disposition can cause variation in oxycodone pharmacokinetic characteristics and decrease or increase the expected clinical response. In forensic medicine, determination of cause of death or assessing time between drug intake and death can be facilitated by knowledge of parent and metabolite concentrations. In this study, the aim was to investigate if CYP2D6 genotyping can facilitate interpretation by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Analgesics, Opioid
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Forensic Genetics

Share to High-Throughput Nucleotide Sequencing

Share to Pharmacogenomic Testing

Share to Young Adult

Source

Identifiers

PMID: 33799050
DOI: 10.1016/j.fsigen.2021.102510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oxycodone findings and CYP2D6 function in postmortem cases.PMID 33799050Read ↗

Pharmacogenomics as molecular autopsy for postmortem forensic toxicology: genotyping cytochrome P450 2D6 for oxycodone cases.Semantic proximity Read ↗

Investigation of morphine and morphine glucuronide levels and cytochrome P450 isoenzyme 2D6 genotype in codeine-related deaths.Semantic proximity Read ↗

Pharmacogenomics for the forensic toxicologist.Semantic proximity Read ↗

Contribution of CYP2D6 Functional Activity to Oxycodone Efficacy in Pain Management: Genetic Polymorphisms, Phenoconversion, and Tissue-Selective MetabolismSemantic proximity Read ↗

Sequencing CYP2D6 for the detection of poor-metabolizers in post-mortem blood samples with tramadol.Semantic proximity Read ↗

Cytochrome P450 2D6 (CYP2D6) genotyping on postmortem blood as a supplementary tool for interpretation of forensic toxicological results.Semantic proximity Read ↗

Utilization of pharmacogenomics and therapeutic drug monitoring for opioid pain management.Semantic proximity Read ↗

Post-mortem SNP analysis of CYP2D6 gene reveals correlation between genotype and opioid drug (tramadol) metabolite ratios in blood.Semantic proximity Read ↗

A fatal doxepin poisoning associated with a defective CYP2D6 genotype.Semantic proximity Read ↗

Pitfalls and challenges associated with phenoconversion in forensic toxcicology.Semantic proximity Read ↗

Interindividual variability in the prevalence of OPRM1 and CYP2B6 gene variations may identify drug-susceptible populations.Semantic proximity Read ↗

Impact of genetic variation in CYP2C19, CYP2D6, and CYP3A4 on oxycodone and its metabolites in a large database of clinical urine drug tests.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.