Article
Roles of nonstructural protein nsP2 and Alpha/Beta interferons in determining the outcome of Sindbis virus infection.
Journal of virology - 1 Nov 2002
Frolova Elena I, Fayzulin Rafik Z, Cook Susan H, Griffin Diane E, Rice Charles M, Frolov Ilya
Abstract excerpt
Alphaviruses productively infect a variety of vertebrate and insect cell lines. In vertebrate cells, Sindbis virus redirects cellular processes to meet the needs of virus propagation. At the same time, cells respond to virus replication by downregulating virus growth and preventing dissemination of the infection. The balance between these two mechanisms determines the outcome of infection at the cellular and...
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