Article
Genome‐wide profiling of humoral immune response to Coxiella burnetii infection by protein microarray
13 Apr 2010
Abstract excerpt
Comprehensive evaluation of the humoral immune response to Coxiella burnetii may identify highly needed diagnostic antigens and potential subunit vaccine candidates. Here we report the construction of a protein microarray containing 1901 C. burnetii ORFs (84% of the entire proteome). This array was probed with Q-fever patient sera and naïve controls in order to discover C. burnetii-specific seroreactive antigens....
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