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Proteome and Antigen Profiling of Coxiella burnetii Developmental Forms

20 Dec 2006

Abstract excerpt

A biphasic developmental cycle whereby highly resistant small-cell variants (SCVs) are generated from large-cell variants (LCVs) is considered fundamental to the virulence of Coxiella burnetii, the causative agent of human Q fever. In this study a proteome analysis of C. burnetii developmental forms was conducted to provide insight into their unique biological and immunological properties. Silver-stained gels of...

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PMID: 17088354
DOI: 10.1128/iai.00883-06

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