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Article

Genetic diversity of the Q fever agent, Coxiella burnetii, assessed by microarray-based whole-genome comparisons.

Journal of bacteriology - 1 Apr 2006

Beare Paul A, Samuel James E, Howe Dale, Virtaneva Kimmo, Porcella Stephen F, Heinzen Robert A

Abstract excerpt

Coxiella burnetii, a gram-negative obligate intracellular bacterium, causes human Q fever and is considered a potential agent of bioterrorism. Distinct genomic groups of C. burnetii are revealed by restriction fragment-length polymorphisms (RFLP). Here we comprehensively define the genetic diversity of C. burnetii by hybridizing the genomes of 20 RFLP-grouped and four ungrouped isolates from disparate sources to...

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Identifiers

PMID: 16547017
DOI: 10.1128/JB.188.7.2309-2324.2006
PMCID: PMC1428397

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