Article
Risk profiles in type 2 diabetes (metabolic syndrome): integration of IL-10 polymorphisms and laboratory parameters to identify vascular damages related complications.
Current pharmaceutical design - 1 Jan 2010
Forte G I, Pilato G, Vaccarino L, Sanacore M, Candore G, Romano G C, Testa R, Franceschi C, Capri M, Marra M, Bonfigli A R, Caruso C, Scola L, Lio D
Abstract excerpt
Recently it has been reported that low serum IL-10 levels are associated with an increased susceptibility for metabolic syndrome and type 2 diabetes mellitus (T2DM). We investigated whether the -1087G/A (rs1800896), -824C/T (rs1800871), -597C/A (rs1800872) IL-10 polymorphisms were associated with type 2 diabetes in a study on a cohort of Italian Caucasians comprising 490 type 2 diabetic and 349 control subjects....
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