Article
Interleukin-10 (-1082G/A) gene polymorphism in patients with type 2 diabetes with and without nephropathy.
Genetic testing and molecular biomarkers - 1 Feb 2012
Erdogan Mehmet, Cetinkalp Sevki, Ozgen Ahmet Gokhan, Saygili Fusun, Berdeli Afig, Yilmaz Candeger
Abstract excerpt
OBJECTIVE: Interleukin (IL)-10 is a major anti-inflammatory cytokine that plays a crucial role in the regulation of the immune system. IL-10 has met the criteria for an anti-inflammatory and an immunosuppressive cytokine, its activity may be important for clinical outcome of diabetic nephropathy (DN). We aimed at evaluating the relation between the genotypic and allelic frequencies of the IL-10 (-1082G/A)...
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