Article
A polymorphism in the visfatin gene promoter is related to decreased plasma levels of inflammatory markers in patients with coronary artery disease.
Molecular biology reports - 1 Feb 2011
Wang Lian-Sheng, Yan Jian-Jun, Tang Na-Ping, Zhu Jun, Wang Yue-Song, Wang Qi-Ming, Tang Jian-Jin, Wang Ming-Wei, Jia En-Zhi, Yang Zhi-Jian, Huang Jun
Abstract excerpt
Visfatin, a newly identified proinflammatory adipokine, has been linked to coronary artery disease (CAD). The -1535C>T polymorphism (rs61330082) located in the visfatin gene promoter is reportedly associated with proinflammatory status. However, it is unclear whether this polymorphism correlates with plasma levels of inflammatory markers including visfatin, hs-CRP, IL-6 and TNF-α in CAD patients. The present...
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