Article
Differential cell surface expression of rhesus macaque's major histocompatibility complex class I alleles Mamu-B*1703 and Mamu-B*0101.
Acta biochimica et biophysica Sinica - 1 Apr 2010
Ouyang Dongyun, He Xianhui, Xu Lihui, Wang Xichao, Gao Qi, Guo He
Abstract excerpt
The major histocompatibility complex class I allele Mamu-B*17 of rhesus macaques is an elite controller of simian immunodeficiency virus (SIV) infection whereas Mamu-B*01 has no inhibitory effect on SIV replication. The mechanism is still elusive. In this study, the so-called "missing G" in the leading peptide sequence of Mamu-B*1703 allele was artificially inserted back through PCR amplification, and the new...
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