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Article

Basal and metal‐induced expression of metallothionein isoform 1 and 2 genes in the RWPE‐1 human prostate epithelial cell line

22 Jun 2007

Abstract excerpt

The human prostate gland has low basal expression of the metallothionein-1 and -2 proteins. In prostate cancer, MT-1/2 protein expression is variable and correlates directly with the increasing Gleason score of the tumor. The goal of the present study was to determine if the RWPE-1 cell line is a good model to elucidate the mechanisms underlying the alterations in MT-1/2 expression that occur during the...

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PMID: 17590860
DOI: 10.1002/jat.1277

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