Article
Evaluation of the chemopreventive potential of retinoids using a novel in vitro human prostate carcinogenesis model.
Mutation research - 20 Sept 2001
Quader S T, Bello-DeOcampo D, Williams D E, Kleinman H K, Webber M M
Abstract excerpt
The prevalence of prostatic intraepithelial neoplasia (PIN) and latent prostatic carcinoma, representing multiple steps in carcinogenesis and progression to invasive carcinoma, makes them relevant targets for prevention. A unique family of human prostate epithelial cell lines, which mimic steps in prostate carcinogenesis and progression, were used to evaluate the chemopreventive potential of all-trans-retinoic...
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