Article
Analysis of multiple candidate genes in association with phenotypes of multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Jun 2010
Sombekke Madeleine H, Arteta David, van de Wiel Mark A, Crusius J Bart A, Tejedor Diego, Killestein Joep, Martínez Antonio, Peña A Salvador, Polman Chris H, Uitdehaag Bernard M J
Abstract excerpt
Multiple sclerosis is a heterogeneous neurological disease with varying degrees of severity. The common hypothesis is that susceptibility to multiple sclerosis and its phenotype are caused by a combination of environmental and genetic factors. The genetic part exerts its effect through several genes, each having modest effects. We evaluated whether disease severity could be predicted by a model based on clinical...
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