Article
Characterization of a beta-hydroxybutyryl-CoA dehydrogenase from Mycobacterium tuberculosis.
Microbiology (Reading, England) - 1 Jul 2010
Taylor Rebecca C, Brown Alistair K, Singh Albel, Bhatt Apoorva, Besra Gurdyal S
Abstract excerpt
The lipid-rich cell wall of mycobacteria is essential not only for virulence but also for survival. Whilst anabolic pathways for mycobacterial lipid biosynthesis have been well studied, there has been little research looking into lipid catabolism. The genome of Mycobacterium tuberculosis encodes multiple enzymes with putative roles in the beta-oxidation of fatty acids. In this report we explore the functionality...
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