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Article

Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d.

Molecular immunology - 1 May 2010

Bhattacharjee Arnab, Lehtinen Markus J, Kajander Tommi, Goldman Adrian, Jokiranta T Sakari

Abstract excerpt

Factor H (FH) regulates the alternative pathway of complement in plasma and mediates discrimination of cellular surfaces to alternative pathway activators and non-activators. The carboxyl-terminal domains 19 and 20 of FH are essential in target discrimination and are known to contain binding site...

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Identifiers

PMID: 20378178
DOI: 10.1016/j.molimm.2010.03.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20378178-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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