Article
A human-specific de novo protein-coding gene associated with human brain functions.
PLoS computational biology - 26 Mar 2010
Li Chuan-Yun, Zhang Yong, Wang Zhanbo, Zhang Yan, Cao Chunmei, Zhang Ping-Wu, Lu Shu-Juan, Li Xiao-Mo, Yu Quan, Zheng Xiaofeng, Du Quan, Uhl George R, Liu Qing-Rong, Wei Liping
Abstract excerpt
To understand whether any human-specific new genes may be associated with human brain functions, we computationally screened the genetic vulnerable factors identified through Genome-Wide Association Studies and linkage analyses of nicotine addiction and found one human-specific de novo protein-coding gene, FLJ33706 (alternative gene symbol C20orf203). Cross-species analysis revealed interesting evolutionary paths...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.