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Article

Ectopic expression of α-synuclein affects the migration of neural stem cells in mouse subventricular zone.

Journal of neurochemistry - 1 Nov 2010

Tani Momo, Hayakawa Hideki, Yasuda Toru, Nihira Tomoko, Hattori Nobutaka, Mizuno Yoshikuni, Mochizuki Hideki

Abstract excerpt

α-Synuclein (α-syn) is a key protein in Parkinson's disease (PD), and its abnormal accumulation is implicated only not in the loss of dopaminergic neurons in the substantia nigra but also in impairment of olfactory bulb (OB) in PD. Olfactory dysfunction could arise from these OB changes as an early symptom in PD. We reported previously the impairment of neuronal stem cell (NSC) proliferation in the subventricular...

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Identifiers

PMID: 20374434
DOI: 10.1111/j.1471-4159.2010.06727.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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