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Article

Genetic and expression analysis of HER-2 and EGFR genes in salivary duct carcinoma: empirical and therapeutic significance.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2010

Williams Michelle D, Roberts Dianna B, Kies Merrill S, Mao Li, Weber Randal S, El-Naggar Adel K

Abstract excerpt

PURPOSE: Salivary duct carcinoma overexpresses epidermal growth factor receptor (EGFR) and HER-2, although the underlying mechanisms remain undefined. Because of the potential utilization of these markers as treatment targets, we evaluated protein and gene status by several techniques to determine complementary value. EXPERIMENTAL DESIGN: A tissue microarray of 66 salivary duct carcinomas was used for...

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Source

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Identifiers

PMID: 20371674
DOI: 10.1158/1078-0432.CCR-09-0238
PMCID: PMC4152860

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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