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Article

HER-2/neu Expression in Salivary Duct Carcinoma: An Immunohistochemical and Chromogenic In Situ Hybridization Study

1 Jan 2008

Abstract excerpt

Salivary duct carcinoma (SDC) shares significant morphologic and immunophenotypic overlap with ductal carcinoma of the breast, including HER-2/neu expression. Previous studies have detected HER-2/neu at the protein level in SDCs; however, no study, to date, has assayed whether this expression is related to gene amplification detected by chromogenic in situ hybridization (CISH). Formalin-fixed, paraffin-embedded...

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PMID: 18091319
DOI: 10.1097/pai.0b013e31802e91b2

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