Article
Differential expression of hormonal and growth factor receptors in salivary duct carcinomas: biologic significance and potential role in therapeutic stratification of patients.
The American journal of surgical pathology - 1 Nov 2007
Williams Michelle D, Roberts Dianna, Blumenschein George R, Temam Stephane, Kies Merrill S, Rosenthal David I, Weber Randal S, El-Naggar Adel K
Abstract excerpt
Salivary duct carcinoma (SDC), a rare malignancy, manifests remarkable morphologic and biologic resemblance to high-grade mammary ductal carcinoma. We contend that, similar to mammary ductal carcinoma, hormones and growth factors may play a role in SDCs. Our aim was to determine the incidence and clinical significance of the expression of several hormone and growth factor receptors and evaluate their potential in...
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