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Article

Expression and mutational status of treatment-relevant targets and key oncogenes in 123 malignant salivary gland tumours.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Oct 2013

Cros J, Sbidian E, Hans S, Roussel H, Scotte F, Tartour E, Brasnu D, Laurent-Puig P, Bruneval P, Blons H, Badoual C

Abstract excerpt

BACKGROUND: Malignant tumours of the salivary glands (MSGT) are rare and pleomorphic entities. Patients with advanced disease may benefit from targeted therapy; however, specific targets for optimising and personalising treatments are yet to be identified. DESIGN: Immunohistochemistry for C-KIT, EGFR, HER2, MUC1, phospho-mTOR, androgen/estrogens/progesterone receptors and Ki67 was carried out and evaluated in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23933559
DOI: 10.1093/annonc/mdt338

Genes

EGFR
HRAS
KIT
BRAF
KRAS
MUC1
NRAS

Provenance

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