Article
Phenotypic and genetic characterization of a unique B lymphocyte deficiency in strain A/WySnJ mice.
European journal of immunology - 1 May 1991
Miller D J, Hayes C E
Abstract excerpt
The elucidation of B lymphocyte development has been partially achieved through genetic models such as the X-linked immunodeficiency (xid) mutation. We discovered a unique B lymphocyte developmental defect in strain A/WySnJ mice. We used single- and two-color flow cytometry to analyze lymphocytes from A/J and A/WySnJ mice. Adult A/WySnJ mice had a severe B cell deficiency, which was apparent in the spleen, lymph...
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