Article
[Ala499Val (C > T) and Lys939Gln (A > C) polymorphisms of the XPC gene: their correlation with male infertility].
Zhonghua nan ke xue = National journal of andrology - 1 Mar 2010
Liang Jie, Lu Chun-cheng, Gu Ai-hua, Xia Yan-kai, Lü Zhong-ming, Xu Jun, Shi Gen-yong, Wang Min-sheng, Wang Xin-ru
Abstract excerpt
OBJECTIVE: The Ala499Val (C > T) and Lys939Gln (A > C) of the XPC gene are two potentially functional nonsynonymous polymorphisms, which affect the rate of DNA repair and might change XPC production and activity. This study aimed to explore the distribution of these two polymorphisms in the Chinese Han population and their relationship with male infertility. METHODS: We genotyped the two polymorphisms of the XPC...
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