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Article

Genetic diversity, determinants, and dissemination of Burkholderia pseudomallei lineages implicated in melioidosis in Northeast Thailand.

Nature communications - 7 Jul 2024

Seng Rathanin, Chomkatekaew Chalita, Tandhavanant Sarunporn, Saiprom Natnaree, Phunpang Rungnapa, Thaipadungpanit Janjira, Batty Elizabeth M, Day Nicholas P J, Chantratita Wasun, West T Eoin, Thomson Nicholas R, Parkhill Julian, Chewapreecha Claire, Chantratita Narisara

Abstract excerpt

Melioidosis is an often-fatal neglected tropical disease caused by an environmental bacterium Burkholderia pseudomallei. However, our understanding of the disease-causing bacterial lineages, their dissemination, and adaptive mechanisms remains limited. To address this, we conduct a comprehensive genomic analysis of 1,391 B. pseudomallei isolates collected from nine hospitals in northeast Thailand between 2015 and...

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Burkholderia infections and melioidosis
Burkholderia pseudomallei
Gene Flow
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genome, Bacterial

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PMID: 38972886
DOI: 10.1038/s41467-024-50067-9
PMCID: PMC11228029

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