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Article

IL-1 production by human thymic dendritic cells: studies on the interrelation with DC accessory function.

Cellular immunology - 1 Jul 1991

Lafontaine M, Landry D, Blanc-Brunât N, Pelletier M, Montplaisir S

Abstract excerpt

Thymic dendritic cells (DC) have been proposed to play a critical role in the generation of immunocompetent T lymphocytes. Since IL-1 is widely considered to be an important second signal in T cell stimulation, we have studied the ability of isolated human thymic DC to produce IL-1. Using the EL4/CTLL conversion assay standardized with recombinant IL-1 beta (rIL-1 beta), we demonstrate that upon LPS-stimulation...

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PMID: 2036677
DOI: 10.1016/0008-8749(91)90288-m

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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