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Article

Efficient stimulation of T cell responses by human IFN-alpha-induced dendritic cells does not require Toll-like receptor triggering.

Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jun 2008

Bracci Laura, Schumacher Reto, Provenzano Maurizio, Adamina Michel, Rosenthal Rachel, Groeper Celia, Zajac Paul, Iezzi Giandomenica, Proietti Enrico, Belardelli Filippo, Spagnoli Giulio C

Abstract excerpt

Dendritic cells (DC) can be activated by proinflammatory cytokines or upon toll-like receptor (TLR) triggering. These stimuli induce specific patterns of phenotypic modulation and gene expression profiles. We investigated whether TLR triggering represents an indispensable requirement for the induction of T cell responses by human DC generated upon culture of monocytes in the presence of granulocyte macrophage...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18463538
DOI: 10.1097/CJI.0b013e318174a52a

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TLR7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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