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Article

Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia.

Nature - 1 Apr 2010

Sigurdsson Torfi, Stark Kimberly L, Karayiorgou Maria, Gogos Joseph A, Gordon Joshua A

Abstract excerpt

Abnormalities in functional connectivity between brain areas have been postulated as an important pathophysiological mechanism underlying schizophrenia. In particular, macroscopic measurements of brain activity in patients suggest that functional connectivity between the frontal and temporal lobes may be altered. However, it remains unclear whether such dysconnectivity relates to the aetiology of the illness, and...

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Identifiers

PMID: 20360742
DOI: 10.1038/nature08855
PMCID: PMC2864584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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