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Article

Epilepsy secondary to tuberous sclerosis: lessons learned and current challenges.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Nov 2010

Moavero Romina, Cerminara Caterina, Curatolo Paolo

Abstract excerpt

BACKGROUND: In tuberous sclerosis complex (TSC), a substantially increased risk of developing epilepsy is present as a result of a disruption of a TSC gene expression in the brain and secondary abnormal cellular differentiation, migration, and proliferation. Dysregulated excitation probably has its roots in the disruption of GABAergic interneuron development. There is an age-dependent electroclinical expression...

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Identifiers

PMID: 20358377
DOI: 10.1007/s00381-010-1128-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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