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Article

Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches.

IUBMB life - 1 Dec 2016

Switon Katarzyna, Kotulska Katarzyna, Janusz-Kaminska Aleksandra, Zmorzynska Justyna, Jaworski Jacek

Abstract excerpt

Tuberous sclerosis complex (TSC) is a rare multi-system disorder, primary manifestations of which are benign tumors and lesions in various organs of the body, including the brain. TSC patients often suffer from epilepsy, mental retardation, and autism spectrum disorder (ASD). Therefore, TSC serves as a model of epilepsy, ASD, and tumorigenesis. TSC is caused by the lack of functional Tsc1-Tsc2 complex, which...

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Identifiers

PMID: 27797139
DOI: 10.1002/iub.1579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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