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Article

A coding variant of the novel serotonin receptor subunit 5-HT3E influences sustained attention in schizophrenia patients.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jun 2010

Lennertz Leonhard, Wagner Michael, Frommann Ingo, Schulze-Rauschenbach Svenja, Schuhmacher Anna, Kühn Kai-Uwe, Pukrop Ralf, Klosterkötter Joachim, Wölwer Wolfgang, Gaebel Wolfgang, Rietschel Marcella, Häfner Heinz, Maier Wolfgang, Mössner Rainald

Abstract excerpt

Sustained attention as measured by the Continuous Performance Test (CPT) has proved a valuable endophenotype for schizophrenia. Recently pharmacological studies suggested a role of the serotonin (5-HT) 3 receptor in schizophrenia. The 5-HT3 receptors are the only ligand-gated ion channels within the 5-HT receptor family. Applying an endophenotype approach, we investigated a potential impact of the genes of the...

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Identifiers

PMID: 20356718
DOI: 10.1016/j.euroneuro.2010.02.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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